徐华娥

发布时间:2020-07-01浏览次数:5659




  徐华娥,威尼斯欢乐娱人v3676高层次引进人才、特聘教授、博导,威尼斯欢乐娱人v3676药剂学系主任,美国MD安德森癌症中心放射肿瘤学系高级访问学者,江苏省第六期“333高层次人才培养工程第三层次培养对象。现任中国抗癌协会纳米肿瘤学分会专委会、中国药学会制药工程专委会经皮给药系统学术研究组、江苏省药学会医院药学专业委员会、江苏省药学会感染药学专业委员会、南京药学会药剂与药理专委会委员,国家自然科学基金优秀青年基金、面上项目及青年基金一审专家,Current Drug Delivery 编委,多个本领域同行评议杂志的审稿人。

  指导第十三届全国大学生药苑论坛创新成果二等奖,第二届生物磁学与磁性纳米材料学术会议暨第九届全国生物与医学纳米技术博士生学术论坛优秀展报一等奖,第四届脑科学与药学前沿高峰论坛青年学者论文Poster比赛三等奖

  长期围绕多功能智能纳米递药平台的构建及在重大疾病(如肿瘤缺血再灌注损伤等)中的应用展开相关研究,主要研究方向:1、基于肿瘤、心脑血管等重大疾病的智能药物递送体系的开发及应用; 2、基因递送及仿生递送等新型纳米药物递送体系的构建的开发及应用;3、医用生物材料研发。作为项目负责人主持国家自然科学基金4项,以第一或通讯作者在 Adv MaterAdv Funct MaterAnal ChemACS Appl Mater InterfacesMater Today Bio等权威期刊上发表论文40余篇。迄今为止,根据Google Scholar统计分析,文章总被引频次1642次,近5年被引频次1079次,单篇最高被引频次217次,H指数22

招生方向:

1.新型药物基因、疫苗递送系统研究与开发

2.药学、药剂学专业

联系方式:

xuhuae@njmu.edu.cn

代表性论文

1.  Wu T#, Lang T#, Zheng C, Yan W, Li Y, Zhu R, Huang X, Xu H*, Li Y*, Yin Q*. Promote intratumoral drug release and penetration to counteract docetaxel-induced metastasis by photosensitizer-modified red blood cell membrane-coated nanoparticle. Adv Funct Mater, 2022, 2212109.

2.  Sun S#, Gu W#, Wu H#, Zhao Q#, Qian S, Xiao H, Yang K, Liu J, Jin Y, Hu C, Gao Y, Xu H*, Liu H*, Ji J*, Chen Y*. Immunostimulant in situ hydrogel improves synergetic radioimmunotherapy of malignant glioblastoma relapse post-resection. Adv Funct Mater, 2022, 32: 2205038.

3.  Wang J#, Wu H#, Zhao Q#, Zou Y, Ding D, Yin H*, Xu H*. Aggregation-induced emission photosensitizer synergizes photodynamic therapy and the inhibition of the NF-κB signaling pathway to overcome hypoxia in breast cancer. ACS Appl Mater Interfaces, 2022, 14: 29613-29625.

4.  Yao Y#, Zhang Y#, Zhang J, Yang X, Ding D, Shi Y*, Xu H*, Gao X*. Azulene-containing squaraines for photoacoustic imaging and photothermal therapy. ACS Appl Mater Interfaces, 2022, 14: 19192-19203.

5.  Wang T#, Wang J#, Jiang H#, Ni M, Zou Y, Chen Y, Wu T, Ding D, Xu H*, Li X*. Targeted regulation of tumor microenvironment through the inhibition of MDSCs by curcumin loaded self-assembled nano-filaments. Mater Today Bio, 2022, 15: 100304.

6.  Zhang Z#, Ji Y#, Hu N#, Yu Q, Zhang X, Li J, Wu F*, Xu H*, Tang Q*, Li X*. Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment. Asian J Pharm Sci, 2022, 17: 751-766.

7.  Zhang M, Wang C, Yang C, Wu H, Xu H*, Liang G*. Using fluorescence on/off to trace tandem nanofiber assembly/disassembly in living cells. Anal Chem, 2021, 93: 5665-5669.

8.  Li X#, Yu N#, Li J, Bai J, Ding D, Tang Q*, Xu H*. Novel “carrier-free” nanofiber codelivery systems with the synergistic antitumor effect of paclitaxel and tetrandrine through the enhancement of mitochondrial apoptosis. ACS Appl Mater Interfaces, 2020, 12: 10096-10106.

9.  Xu H#, Wang T#, Yang C, Li X*, Liu G, Singh PK, Krishnan S*, Ding D*. Supramolecular nanofibers of curcumin for highly amplified radiosensitization of colorectal cancers to ionizing radiation. Adv Funct Mater, 2018, 28: 1707140.

10. Yu CY#, Xu H#, Ji S, Kwok RT, Lam JW, Li X*, Krishnan S, Ding D*, Tang BZ*. Mitochondrion-anchoring photosensitizer with aggregation-induced emission characteristics synergistically boosts the radiosensitivity of cancer cells to ionizing radiation. Adv Mater, 2017, 29: 1606167.


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